The total number of ways possible are,
[tex]\begin{gathered} Total\text{ ways = 4 }\times\text{ 2 }\times\text{ 2 } \\ Total\text{ ways = 16} \end{gathered}[/tex]Where,
4 = 4 blood groups
2 = 2 Rhesus factors
2 = Gender
Thus there are 16 ways possible.