SOLUTION
Looking at the sequence 15, 16, 18, 21, ?, ?, ?, ?, 51, 60, 70, 81
The next number is gotten by increasing the number added by 1. That is
[tex]\begin{gathered} 15+1=16 \\ 16+2=18 \\ 18+3=21 \\ 21+4=25 \\ 25+5=30 \\ 30+6=36 \\ 36+7=43 \\ 43+8=51 \\ 51+9=60 \\ 60+10=70 \\ 70+11=81 \end{gathered}[/tex]So, the missing numbers are 25, 30, 36, 43