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Recombination can separate linked genes: Crossover, or recombination, happens when two homologous chromosomes align during meiosis and exchange a portion of genetic material.

The alleles for gene C were swapped in this case. As a result, there are two recombinant chromosomes and two non-recombinant chromosomes. During prophase I of meiosis, two distinct chromosomes trade fragments of genetic information when they cross over. Crossing over is more frequent if the related genes are located widely apart on the chromosome. Crossing across is referred to as recombination. Recombination can happen between any two genes on a chromosome; the quantity of crossing over depends on how close the genes are on the chromosome.

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