The fluidity of a membrane allows multiple membrane proteins to diffuse rapidly in the plane of the bilayer and interact with one another, which is important in cell signaling, for example.
Maintaining appropriate membrane fluidity is critical for all cells for a variety of reasons. Cell membranes must maintain a balance between fluidity, which allows proteins and lipids to move inside the membrane, and membrane curvature, bending, budding, and fusing, without compromising membrane integrity and enabling substances to leak into or out of the cell. The function of biomolecules residing within or connected with the membrane structure is known to be affected by membrane fluidity. Some peripheral proteins, for example, rely on membrane fluidity to bind.
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