For monosaccharides to cyclize, an alcohol group must attack a carbonyl group, the carbon of linear pento-ketose has the reactive carbonyl is the carbon number 1.
What is a monosaccharide?
The monosaccharide is a single unit sugar. Recall that sugars could have cyclic or open chain structures. It is possible for the compound to exists in either the cyclic or the open chain structure.
Now, for monosaccharides to cyclize, an alcohol group must attack a carbonyl group, the carbon of linear pento-ketose has the reactive carbonyl is the carbon number 1.
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