Southerners wanted to annex Texas to the United States in order to expand slavery. Northerners opposed annexation because they feared that annexing more slave territory would tip the Senate's uneasy balance in favor of slave states—-and spark a war with Mexico, because Mexico did not recognize Texas' independence, so annexation could spark a war.
Although Texans voted for annexation by the US, the Andrew Jackson and Martin Van Buren administrations rejected the proposal.
The rejection was attributed to constitutional concerns and a fear of war with Mexico, but antislavery sentiment in the United States undoubtedly influenced Van Buren and remained the main impediment to annexation.
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