Released neurotransmitters are cleared from the synaptic cleft by enzymatic destruction and diffusion .
The possible methods/mechanisms are
- Neurotransmitters are removed from the synaptic cleft by special transporter proteins on the pre-synaptic membrane.
- Sometimes after interacting with the post synaptic receptors to allow another around of synaptic transmission.
- Simple diffusion of the transmitter molecules away from the synapse is another way of clearing released neurotransmitter from the cleft.
the neurotransmitter action can be terminated by enzymatic destruction in the synaptic cleft
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