The matrix of connective tissues consists of fibers and a ground substance of various densities and consistencies.
In typical connective tissue, the ground substance is water that has been stabilized by glycosaminoglycans, proteoglycans, and glycoproteins. Minerals are part of the ground material in bone.
The ground substance in the blood is liquid (plasma). Collagen, reticular, and elastin fibers make up both loose and dense connective tissue.
The most prevalent kind of connective tissue cells is fibroblasts. They create both fibers and amorphous ground material. The extracellular matrix's "ground substance" is an amorphous, gelatinous substance.
It fills the gaps between fibers and cells and is clear and colorless. In reality, it is made up of giant molecules called glycosaminoglycans (GAGs), which join to produce proteoglycans, which are much bigger.
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