Two monosaccharide isomers with 4 chiral carbons in which the configuration of one chiral carbon differs are most precisely described Diastereomers
Stereoisomers are up two types such as diastereomers and enantiomers.
Diastereomers or diastereoisomers are the type of non-mirror image non-identical stereoisomers. They are non-superimposable.
For example in D-glucose and D-altrose, although have the same number and type of atoms but the arrangement is different.
On the other hand, though Enantiomers are non-superimposable, but the only difference is that they are mirror images of each other.
Hence, in this case 4 chiral carbons of two sugar isomers where the configuration of one chiral carbon differs are Diastereomers
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