Secretin is a 27 amino acid polypeptide hormone produced by S cells of the duodenum in response to a pH between 2 and 4.5 (very acidic).
Secretin is a 27 amino acid polypeptide hormone produced by S cells of the duodenum in response to a pH between 2 and 4.5. Upon reaching the duodenum, the chyme will be covered with pancreatic juice from the pancreas and with a pH close to 9 thanks to the presence of sodium bicarbonate.
inhibiting gastric activity and activating the secretion of enzymes and bicarbonate by the pancreas, and of bicarbonate and bile salts by the liver.
With this information, we can conclude that Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions
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