The lock and key model states that the active site of an enzyme has a Rigid shape while the induced fit model describes the active site as having a flexible shape.
According to the "lock and key" theory, an enzyme's active site precisely matches a particular substrate. According to the induced fit concept, an enzyme's active site will alter conformation when it binds a substrate to enhance the fit. The enzyme behaves as a lock in this concept, while the substrate acts as a key. Therefore, it states that only the proper key will fit in the active site of the enzyme. The active sites that are already existent have a rigid substrate form that only reacts with substrates that exactly fit inside of them.
Induced Fit Model: In this kind of model, the ultimate product of the enzyme is partially determined by its substrate, and enzymes are viewed as flexible.
Lock and Key claim that no modifications are required and that just a particular kind will fit. However, according to induced fit, the active site will alter to aid substrate fit.
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