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IgG is the antibody normally constituting the highest percentage of antibodies in the blood.
What are antibodies?
- Antibodies also known as immunoglobulin, are the proteins that are protective in nature and are produced by the immune system.
- Antibodies are large, Y-shaped and are attached to the antigens like bacteria, viruses, etc. and they eliminate these from the body.
- Antibodies are produced by specialized white blood cells i.e., B-cells.
- There are five types of antibodies -IgG, IgM, IgA, IgD, and IgE.
- IgG is one of the most common antibody found in the blood and tissue fluids which makes around 70% - 75% of all immunoglobulins in the body.
- IgG function is to protect the body from the viral and bacterial infections.
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Immunoglobulin G is the antibody that normally constitutes the highest percentage of antibodies in the blood.
What is an antibody?
- Antibodies are proteins made by plasma cells as a result of a response to an antigen.
- Antibodies are antigen-specific that can attach to only specific antigens to destroy them.
- They are found mainly in the blood and other tissues and extracellular fluids.
- Antibodies are found in the B cells of lymphocytes used to attack invading bacteria and viruses that are toxic.
What is immunoglobulin G?
- There are 5 classes of immunoglobulins that are IgG, IgA, IgD, IgM, and IgE.
- Immunoglobulin G represents 75% of antibody serum in a body.
- IgG is produced by plasma B cells to fight bacteria, viruses, and toxins.
- Each IgG has two paratopes which are antigen-binding sites. These paratopes recognize an antigen and bind to it.
- The Y-shaped IgG has identical paratopes in each arm.
- IgG recognizes the pathogens and causes immobilization. They also bind and neutralize toxins.
- IgG is also involved in allergic reactions.
- Their function includes opsonization which enables them to bind with bacterial surface facilitating their phagocytosis.
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