Question

What must happen in order for a chemical signal to change the membrane potential of a neuron?

Answer 1

A Final statement or concluding statement

1. The ion flux across the membrane must vary.
2. The number of open ion channels must be altered.

How does a neuron change its membrane potential?

The membrane potential is altered by opening and shutting ion channels.

The resting membrane potential of a neuron is closer to the potassium equilibrium  potential than to the sodium equilibrium potential. That's because the resting membrane is much more permeable to K+ to Na+. Changing the number of open ion channels allows you to alter the  membrane potential of the cell and generate electrical signals.

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