When endothelial cells are injured, alteration contributes to atherosclerosis are increased endothelial permeability, platelet aggregation, leukocyte adhesion, and generation of cytokines.
A small, disc-shaped cell fragment present in the blood and spleen. Platelets are fragments of megakaryocytes, which are very large cells in the bone marrow. They aid in the formation of blood clots, which slow or stop bleeding and aid in the healing of wounds.
Platelets, also known as thrombocytes, are minute, colorless blood cell fragments that form clots and stop or prevent bleeding. Our bone marrow, the sponge-like substance inside our bones, produces platelets. Stem cells in bone marrow turn into red blood cells, white blood cells, and platelets.
When your platelet count goes below 10,000 platelets per microliter, you may experience dangerous internal bleeding. Though uncommon, severe thrombocytopenia can result in catastrophic brain hemorrhage.
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