Intraneuronal effect on its effector organ is that it can excite or inhibit.
Some interneurons receive recurrent collaterals from axons (e.g., LMN axons) and project back onto the dendrites or cell body of origin of that axon, usually inhibiting that neuron. This process can help to regulate the excitability and timing of excitation of the target neurons.
The excitability of an interneuron network is bidirectionally controlled by distinct epochs of activity in principal cells. Examples of excitatory neurotransmitters include glutamate, epinephrine and norepinephrine.
Inhibitory neurotransmitters block or prevent the chemical message from being passed along any farther. Gamma-aminobutyric acid (GABA), glycine and serotonin are examples of inhibitory neurotransmitters.
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