The activation of the serine/threonine protein kinase akt requires phosphoinositide 3-kinase (pi 3-kinase) to create phosphorylated lipids that serve as docking sites that localize Akt to the plasma membrane.
Ak strain changing is the meaning of the word Akt. The term "Akt" first appeared in 1928, when J. Furth conducted research on mice that spontaneously generated thymic lymphomas.
An essential enzyme in the signaling pathway that controls how cells react to insulin as well as other growth stimuli is called phosphoinositide 3-kinase (PI3K). To create phosphatidyl-inositol-3,4,5-trisphosphate (PIP3) at the plasma membrane, one such enzyme phosphorylates phosphatidylinositol-4,5-bisphosphate in the third carbon in the molecule.
Therefore, The activation of the serine/threonine protein kinase akt requires phosphoinositide 3-kinase (pi 3-kinase) to create phosphorylated lipids that serve as docking sites that localize Akt to the plasma membrane.
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