The ability of an analytical method to assess small variations in the concentration of analyte is referred to as: Analytical senstivity.
The ability of the test to detect very low concentrations of a certain substance in a biological sample. Analytical sensitivity is often referred to as the limit of detection (LoD). LoD is the true concentration of the analyte in the sample that can be consistently detected ≥ 95% of the time. The precision of an analytical method is the proximity of a series of individual analyte measurements that are applied repeatedly to multiple sample portions of the same sample. It is calculated as a relative standard deviation.
Specificity is the ability to unambiguously assess the analyte for the presence of components that could be expected to be present. In general, they can include impurities, decomposers, substrates, etc. The lack of specificity of an individual analytical procedure can be compensated by other additional analytical procedures.
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