Liquid cultures that are grown with the continual or periodic addition of fresh media over time are called continuous cultures.
Continuous cultures are used to reproducibly culture microorganisms at submaximal growth rates under various growth constraints such that culture conditions remain substantially constant (“steady state”) for long periods of time. It is a set of technologies that
A “continuous culture” system is envisioned, in which bacteria grow in a constant volume of liquid medium that is continuously renewed. If the renewal rate (percentage of medium renewed per unit time) is equal to the growth rate.
For example, cell cultures maintained in the log phase are best when a constant cell supply is required. Therefore, conditions should be constantly monitored and adjusted accordingly to prevent cells from entering the stationary phase (see bacterial growth curves).
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