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Prostaglandins locally acting chemicals are derived from arachidonic acid.

What does arachidonic acid produce?

  • Arachidonic acid is then quickly transformed into active metabolites, including prostaglandins, prostacyclin, and thromboxanes by cyclooxygenases and leukotrienes by lipoxygenases Page et al (2006).
  • These metabolites' physiological effects are numerous and varied.

Is prostaglandins a local hormone?

  • Prostaglandins are the most diversified group of eicosanoids and are believed to be produced in the majority of bodily tissues.
  • This particular local hormone activates the inflammatory response and pain receptors.

What is arachidonic acid found in?

  • Arachidonic acid can be found mainly in the fatty parts of meats and fish (largely red meat), so vegetarians usually have lower levels of arachidonic acid in the body than those with omnivorous diets.
  • There is a great deal of controversy about arachidonic acid.

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