Streptomycin is an antibiotic that interferes with the function of the 30s subunit of the prokaryotic ribosome. when it's treated on bacteria it reacts by binding to the site where tRNA typically binds, an anticodon.
Streptomycin, interferes with ribosomal activities and inhibits bacterial protein synthesis in vitro. Streptomycin can fit into the binding site for anticodons and interfere with the binding site for tRNA derivatives due to the structural similarities between it and the anticodon.
For instance, it prevents polypeptide synthesis triggered by either synthesised polynucleotides or natural mRNA3-5, leading to significant genetic code misinterpretation in the latter scenario. The medication also causes polysomes to break down and releases fMet-tRNA from interacting with the 70S ribosome.
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