Question

Resting membrane potential depends on: i. differential distribution of ions across the axon membrane ii. the opening of voltage-gated calcium channels iii. active transport of ions across the membrane

Answer 1

Resting membrane potential depends on differential distribution of ions across the axon and active transport of ions across the membrane.

What is resting membrane potential?

• Resting membrane potential is the static potential difference between the inside of the cell to outside due to the differential distribution of ions on both side of the membrane.
• It is due to uneven distribution of ions, differential permeability of membrane to the ions and the activity of ion channels like Na+ and K+ channel.
• During the resting membrane potential, a cell is at rest and does not carry any signal.
• The value of resting membrane potential varies in different cell types.
• In a typical nerve cell, value of resting membrane potential is -70mV.
• When the cells are excited, membrane potential changes drastically for few milliseconds and is called action potential.

Learn more about resting membrane potential here:

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