The laboratory immunologic assessment of Waldenstrom's primary macroglobulinemia differs from other monoclonal gammopathies due to the increased generation of IgM antibodies.
Antibodies are molecules generated by specific cells of the immune system that act to recognize antigens during adaptive immune responses.
Moreover, IgM antibodies are special antibodies that have a major function as modulators of immunological tolerance.
In conclusion, the laboratory immunologic assessment of Waldenstrom's primary macroglobulinemia differs from other monoclonal gammopathies due to the increased generation of IgM antibodies.
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