Olfactory receptors would play the biggest part in alerting you when you have forgotten to wash your gym socks for 3 weeks.
Olfactory receptor, often known as the "smell receptor," is a protein that can bind odor molecules and is essential for the perception of smell (olfaction). Arthropods, terrestrial vertebrates, fish, and other creatures all share these receptors. Airborne odor molecules that reach the nasal cavity and bind to olfactory receptors can be detected by olfactory receptors.
The bipolar neurons themselves are specialized because each olfactory sensory neuron has a single type of receptor on its cilia, and those receptors are designed to detect particular odorants. The hypothalamus receives information from the olfactory tracts. In the mucus, odorants break down and attach to receptors. The olfactory bulbs get impulses from mitral cells.
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