(a) The gas of interstellar medium can be detected from the radiations of photons of wavelength 21 cm.
(b) The gas of interstellar medium can be detected from the absorption lines present in the light from distant stars, which must be caused by a medium of density and temperature other than that of the stars emitting the lights.
Interstellar medium is the matter and radiation that exist in the space between the star systems in a galaxy.
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