The correct answer is option E
The amyotrophic lateral sclerosis is a medical condition in which the brain cells (nerve cells) is involved. The nerve cells of the brain and spinal cord gets affected.
In this disease the muscles of hands and legs have trouble in moving as the motor nerve gets demise. It is a well known fact that when the motor nerves generates or dies the muscles do not function properly as the brain does not initiates the muscle movement.
In severe cases the ability to speak is also lost along with the voluntary movement of the muscles.
