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Most enzymes in the human body work best at 37C (98.6F). When you get sick, sometimes you get a fever, what do you think this means for your enzymes?

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Answer:

Because enzymes are denatured by heat, fevers can cause changes in enzymatic structure and shape. If your fever is high enough to fully denature your enzymes, this can lead to death by preventing your enzymes from catalyzing necessary reactions.

Hope this helps :D

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