Biofilms are resistant to antimicrobial chemicals due to genetic diversity.
Biofilms are considered as a reservoir of genetic diversity. The emergence and spread of antibiotic resistance genes increase in biofilm due to horizontal gene transfer (HGT).
HGT can happen through the transfer of plasmids among microorganism cells in a biofilm through conjugation so that's why the antimicrobial resistance is higher in a biofilm than in free-floating bacterial cells.
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