In relation to whether either Myra or Connie will be bound to the transaction involving the house, the answer is no because the subject matter has been destroyed.
Why are neither party bound to the contract?
The subject matter of the contract which is the house, has been destroyed and this happened before the contract was finalized.
There is therefore, no longer a subject for the contract to be finalized and as it is neither party's fault, neither of them will be bound by the contract's terms.
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