Question

In the general population, 1/150 people are carriers for the allele for Tay-Sachs disease. A child with the disease is born to healthy parents who are unaware of their carrier status. The allele that prevents the disease in the parents is a ______ allele and the one that causes the disease is a ______ allele.

Answer 1

The allele that prevents the disease in the parents is a WILD TYPE allele and the one that causes the disease is a MUTANT allele. An allele is a gene variant.

Alleles and diseases

An allele is a gene variant, in diploid organisms (like humans) two alleles are inherited for each gene locus.

A wild-type allele is an allele that produces a normal phenotype.

Conversely, a mutant allele is associated with a defective phenotype in disease and/or genetic conditions.

Learn more about mutant alleles here:

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