Which of the following correctly explains where DNA replication will begin on the strand oriented 5'â†’3', reading from left to right? DNA replication will be randomly initiated along the unwound portion of the DNA strand since base pairing will occur. Answer A: D N A replication will be randomly initiated along the unwound portion of the D N A strand since base pairing will occur. A DNA replication cannot occur since there is already RNA base pairing with the template strand.

The process of DNA replication is ALWAYS started immediately to the left of the RNA because DNA polymerase is an enzyme that needs RNA primer. It is required the presence of a primase for this process.

DNA replication and primase

DNA replication is always initiated by a specific RNA polymerase referred to as primase.

Primase is an RNA polymerase that generates a short RNA oligonucleotide known as primer, which is complementary to the DNA strand.

Subsequently, DNA replication is started immediately to the left of this RNA primer where DNA polymerase adds nucleotides to the growing DNA strand.

In conclusion, the correct (and missing) statement here is 'the process of DNA replication is ALWAYS started immediately to the left of the RNA because DNA polymerase is an enzyme that needs RNA primer'.

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