The words small and little are synonym in literal sense, but it depends on how you use them in a sentence.
Well, yes you can use both small and little to mean the same thing in a sentence, but when it comes to amount, it's specifically little
You can say " I have little water to drink"
but you can never say " I have small water to drink"
Small is mostly used to describe size, e.g I have a small water bottle.