Question

An man about 80 years old, lives alone. He looks very weak and undernourished. His lower limbs bones are tender and thin. Due to poor diet and loneliness, he lacks the essential vitamins and minerals for his bone formation. Explain bone formation (ossification) , and bone marrow formation which this man is lacking.​

Answer 1

$\large \text{Answer}$

All bone formation is a replacement process. During development, tissues are replaced by bone during the ossification process. In intramembranous ossification, bone develops directly from sheets of mesenchymal connective tissue. In endochondral ossification, bone develops by replacing hyaline cartilage, bone formation, also called ossification, process by which new bone is produced. ... Soon after the osteoid is laid down, inorganic salts are deposited in it to form the hardened material recognized as mineralized bone. The cartilage cells die out and are replaced by osteoblasts clustered in ossification centres.

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