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the development of which type of microscope made it possible to create high-resolution three-dimensional images of living cells

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Cryo-electron microscopy (cryo-EM), or electron cryomicroscopy, is a form of transmission electron microscopy (TEM) where the sample is studied at cryogenic temperatures (generally liquid-nitrogen temperatures). Cryo-EM is gaining popularity in structural biology.

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The development of which type of microscope made it possible to create high-resolution, three-dimensional images of living cells?

confocal microscope