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Most differential diagnoses include a physical exam and a health history. During a health history, you'll be asked about your symptoms, lifestyle, and previous health problems. You'll also be asked about your family's health problems. Your provider may also order lab tests for different diseases. Lab tests are often done on blood or urine.

If a mental health disorder is suspected, you may get a mental health screening. In a mental health screening, you will be asked questions about your feelings and mood.

The exact tests and procedures will depend on your symptoms.

For example, you may see your health care provider because you have a skin rash. Rashes can be caused by a wide variety of conditions. Causes can range from mild allergies to life-threatening infections. To make a differential diagnosis of a rash, your provider may:

Do a thorough exam of your skin

Ask you if you been exposed to any new foods, plants, or other substances that could cause an allergy

Ask about recent infections or other diseases

Consult medical text books to compare your how your rash looks to rashes in other conditions

Perform blood and/or skin tests

These steps can help your provider narrow down the choices of what is causing your rash.

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