Question

You learned in the previous lesson that T cells require two independent signals to become activated. When T cells are activated, they acquire effector functions and begin to proliferate. This two-signal mechanism prevents the expansion of self-reactive effector T cells. Similarly, B cell receptor signaling alone is not sufficient to activate B cells. B cells require assistance from helper T cells to become activated by monovalent protein antigens and gain certain immune functions. What changes do you suspect will occur to B cells when they are activated by protein antigen and receive T cell help? (select all that apply)
a) They will generate memory cells that can respond to a subsequent exposure to antigen.
b) Their immunoglobulin genes will be mutated in a way that alters antigen affinity.
c) The isotype of their immunoglobulin (Ig) genes will change.
d) They will proliferate and expand.
e) They will secrete antibodies.

Answer 1

Answer:

a. They will generate memory cells that can respond to subsequent exposure to antigen.

d. They will proliferate and expand

e. They will secrete anti bodies

Explanation:

B cells are type of white blood cells who belong to lymphocyte subtype. They are activated by binding of antigen to receptors on cells surface, against which they initiate and antibody response. Some of these cell proliferate and divide while other become long lived memory cells that respond subsequent exposure to antigen at later stage.