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They are bad for people in large quantities, which is known as an overdose. A drug or alcohol overdose happens when a person consumes a lethal or toxic amount of an addictive substance, poisoning the body. An overdose may be accidental or may be a deliberate attempt to end their life.  Each class of drugs has a unique effect on the brain and body, causing death by overdose for different reasons.

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https://www.bluecrestrc.com/how-do-overdoses-kill/

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