Step-by-step explanation:
[tex]6 {x}^{2} {y}^{3} - 2x + 10 \\ when \: x = 5 \: y = - 3 \\ 6( {5})\: ^{2} ( { - 3})^{3} - 2(5) + 10 \\ 6 (25)( - 27) - 10 + 10 \\ = - 4050[/tex]
