Temperature and pH levels can influence microbial infections in the body.
Microbes have their optimum pH and temperature conditions in which they can function properly . They can survive in particular range of pH and temperature.
If the conditions in human body do not match the range in which they can exist , the microbes will not be able to grow or reproduce and they'll ultimately die.
pH and temperature outside the adequate range ( for microorganism) may cause denaturation of proteins and enzymes of the microorganism which will lead to their death.
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