Answer: Sickle cell disease affects millions of people around the globe and is the 4th leading cause of death in children in many developing countries like Africa. It causes health problems like anemia, swelling, bacterial infections Sickle cells that block blood flow to organs deprive the affected organs of blood and oxygen. In sickle cell anemia, blood is also chronically low in oxygen. This lack of oxygen can damage nerves and organs, including your kidneys, liver, and spleen. The sickle cell mutation is relevant to malaria because infection of a red blood cell with the malaria parasite leads to hypoxia. People develop sickle-cell disease, a condition in which the red blood cells are abnormally shaped if they inherit two faulty copies of the gene for the oxygen-carrying protein hemoglobin. The faulty gene persists because even carrying one copy of it confers some resistance to malaria. Sickle cell disease is more common in Hispanic-Americans from Central and South America. People of Middle Eastern, Asian, Indian, and the Mediterranean. Most of the different air pollutants are closely intercorrelated, and increasing overall levels seem to correlate with increased hospital attendance, although higher concentrations of atmospheric carbon monoxide may offer some benefit for patients with sickle cell disease.
Explanation: Some of it is in my own words but make sure to read it over and paraphrase. good luck!! :)
