When the twitching pink nose of a mouse detects danger, the animal has to act fast. Fortunately, a predator rapidly triggers the release of stress hormones in the mouse and prompts behaviors that reduce the risk of it becoming the predator’s latest snack. helping explain how the brain translates danger signals detected by the nose into a physiological response. The research offers clues to the larger puzzle of how animals, including humans, perceive and respond to fear.