Question

Indicate whether each of the following occurs mainly in G1 phase (G), S phase (S), or G2 phase (H) of the cell cycle. Your answer would be a four-letter string composed of letters G, S, and H only, e.g. HGSS. ( ) DNA helicase activation ( ) DNA helicase deposition on DNA at the replication origins ( ) ORC phosphorylation ( ) Licensing of replication origins

Answer 1

Answer:

the answer is S-G-S-G  

Explanation:

DNA helicases are enzymes that catalyze the unwinding of the double DNA helix in order to form a replication fork at the origin of replication (i.e., the site where DNA replication starts). DNA replication occurs in a bi-directional manner by two replication forks that move in opposite directions in order to form a replication bubble. The origin of replication is formed during the transition from mitosis to G1 when they are licensed for the subsequent S phase. The origin recognition complex (ORC) is a DNA binding complex that binds to the origin of replication, whose function is to act as a scaffold for the assembly of initiation factors. ORC is phosphorylated during the beginning of the S phase in order to dissociate this complex from chromatin.