Answer:
1. artificial is done by humans, doesn't result in evolution or speciation and is a faster process
natural is random changes in the genotype of an organism that increase the change of the organism surviving and procreating thus passing on their genotype to the next generation
2. both can result in genotype and phenotype changes within a population
3. the environment and organisms are in constant relationship, as the environment changes the individual organisms within that environment that are best suited in a heritable way will survive and procreate more thus increasing the suitability of the population to the current environment
4. anytime a species is not able to replace it's numbers successfully, could be caused by environmental changes, predation pressures etc
Explanation: