Question

16. Which of the following affect(s) the distribution of a drug?

A. Excretory functions
B. Fat solubility and protein-binding ability
C. The rate of metabolism
D. The functioning of the liver and kidneys

Stuck on this one plz help
It’s not C- got the it wrong

Answer 1

Answer:

B. Fat solubility and protein-binding ability

Explanation:

Both protein binding and altered pH of extracellular fluids affect drug distribution. The presence of food in the gastrointestinal tract affects drug absorption, whereas an increasing hepatic enzymes affects drug metabolism. High blood levels are not known to affect drug pharmacokinetics. Page 4

Answer 2

Answer:

its B.

Explanation:

This is because everyones body is different and everyone has different percentages of body fat. An example is consuming alcohol. When someone who is a bit more overweight, they will have to consume more to get to the "same level" as someone who has an average percentage of body fat. same goes for people who are under-weight. They consume less to be at that "same level"