Question

Indicate whether each of the following statements about the heme-binding site in myoglobin is true or false. If you think a statement is false, explain why.

a. The proximal histidine covalently binds iron.
b. The distal histidine covalently binds oxygen.
c. The distal histidine binds iron
d. Free heme binds CO with the Fe, C and O atoms in a linear array.
e. The iron in heme binds the oxygen atom of CO

Answer 1

a) true
b)true
c) False, the distal histidine binds oxygen by hydrogen bonding interaction.
d) true
e) true