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Answer:
Cold boxes are used to collect and transport vaccine supplies from one fixed vaccine store to another, and from vaccine stores to health facilities. They are also used to temporarily store vaccines when the refrigerator is out of order or being defrosted.
Depending on the model, cold boxes can be used to store vaccines for periods of up to two days or more when there is no electricity available, when the health facility refrigerator is out of order, or when a passive container is needed while the refrigerator is being defrosted.