The extracellular matrix is composed of many proteins with different functions. One of them is Fibronectin. The loss of Fibronectin in the extracellular matrix would result in a lack of adhesion.
What is the connective tissue?
- The connective tissue is composed of cells notoriously separated by the abundant extracellular matrix.
- The different connective tissues differ from each other in the properties of their matrix.
What is the extracellular matrix?
- The extracellular matrix is produced by fibroblasts, which is a predominant cell population.
- The extracellular matrix has fibrillar proteins of different nature such as collagen, fibrillin, and elastin that determine tension properties.
- There are also adessive proteins such as fibronectin and laminin.
- These proteins are included in a medium containing water, salts, GAGs, proteoglycans, glycoproteins, and other macromolecules. All of them confer turgidity and facilitate diffusion.
According to this framework, the loss of Fibronectin in the extracellular matrix would result in lack of adhesion.
You can learn more about the extracellular matrix at
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