Answer:
Like most chemical reactions, the rate of an enzyme-catalyzed reaction increases as the temperature is raised. A ten degree Centigrade rise in temperature will increase the activity of most enzymes by 50 to 100%. Variations in reaction temperature as small as 1 or 2 degrees may introduce changes of 10 to 20% in the results. In the case of enzymatic reactions, this is complicated by the fact that many enzymes are adversely affected by high temperatures. As shown in Figure 13, the reaction rate increases with temperature to a maximum level, then abruptly declines with further increase of temperature. Because most animal enzymes rapidly become denatured at temperatures above 40°C, most enzyme determinations are carried out somewhat below that temperature.Over a period of time, enzymes will be deactivated at even moderate temperatures. Storage of enzymes at 5°C or below is generally the most suitable. Some enzymes lose their activity when frozen.
A person has a high fever of 105F. an effect that such a high fever would likely have on enzymatic activity is denaturing enzymes in the nervous system, possibly causing epileptic seizures.
High fever (above 100F) is very dangerous for humans and can be fatal. One of the causes of this problem is the fact that high temperature modifies enzymes in the central nervous system.
How can high fever modify these proteins?
a) Inducing the modification of the amino acid sequence of the enzymes.
With this information, we can conclude that a person has a high fever of 105F. an effect that such a high fever would likely have on enzymatic activity is denaturing enzymes in the nervous system, possibly causing epileptic seizures.
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