Question

Which RNA sequence will result from the transcription of the DNA sequence AAT TTC CGA ATG GGA?

A. UUA AAG GCU UAC CCU

B. AGG GTA AGC CTT TAA

C. TTU UUG GCT TUC CCT

D. AAU UUC CGA AUG GGA

Answer 1

Answer:

A. UUA AAG GCU UAC CCU

Explanation:

Transcription is the first process of Gene expression, which involves the synthesizing of a mRNA molecule from a DNA strand. This process (transcription) which is carried out or catalyzed by an enzyme called RNA polymerase, uses the complementary base pairing rule to synthesize nucleotides.

The complementary base pairing rule as proposed by Chargaff states that Adenine base (A) should bond with Thymine base (T). Likewise for Guanine (G) and Cytosine (C). Hence, in a DNA strand with sequence: AAT TTC CGA ATG GGA, the following RNA will result:

UUA AAG GCU UAC CCU.

Note that, Uracil base replaced Thymine base in the mRNA molecule.

Since; A-U and G-C

AAT TTC CGA ATG GGA ---------- DNA

UUA AAG GCU UAC CCU --------- RNA

Answer 2

The RNA sequence that will result from the transcription of the DNA sequence AAT TTC CGA ATG GGA is UUA AAG GCU UAC CCU (Option A).

• During transcription, a fragment of nucleotide DNA sequence (usually a gene) is used as a template to encode a complementary RNA sequence, usually a messenger RNA (mRNA).

• Subsequently, this mRNA is in turn used as a template to synthesize a protein by a mechanism known as translation.

• According to the base pair rules, Thymine always pairs with Adenine, whereas Guanine always pairs with Cytosine.

• In RNA, Thymine (T) bases are replaced by Uracil (U) containing bases.

In conclusion, the RNA sequence that will result from the transcription of the DNA sequence AAT TTC CGA ATG GGA is UUA AAG GCU UAC CCU (Option A).

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