How does the anaphase stage differ in the two phases of meiosis?. . Select one of the options below as your answer:. . . . A.. Anaphase I separates sister chromatids and anaphase II separates homologous chromosomes into daughter cells.. . . . . B.. Anaphase I has homologous chromosomes attached to spindle fibres and anaphase II involves separation of these homologous chromosomes.. . . . . C.. Anaphase I separates homologous chromosomes and anaphase II separates sister chromatids into daughter cells.