Answer:
The outbreak of the smallpox epidemic helped the Spanish conquistadors defeat and rule over the Native Americans.
Explanation:
The Spaniards under conquistador Hernán Cortés were on an expedition to Mexico when they encountered the Aztecs. But despite their lesser number of supporters, he was able to defeat the whole city without much help needed.
The help came in the form of an epidemic, the spread of small-pox that killed almost half of the whole population. It spread from within the territory, fatally decreasing the whole population, reducing the people to a much lesser number which became an advantage for the conquistadors. This ironically helped in favoring the stance of Cortés and his men, helping in the defeat of the city.
Thus, the natural cause that played an important role in the defeat of the Native American people was the outbreak of small-pox and the deaths that resulted.
